Categoria
Ketoconazol [Inn-Spanish]
Nombres de marca,
Ketoconazol [Inn-Spanish]
Analogos
Ketoconazol [Inn-Spanish]
Marca los nombres de mezcla
No information avaliable
Ketoconazol [Inn-Spanish]
Formula quimica
C26H28Cl2N4O4
Ketoconazol [Inn-Spanish]
RX enlace
http://www.rxlist.com/cgi/generic/ketocon.htm
Ketoconazol [Inn-Spanish]
FDA hoja
Ketoconazol [Inn-Spanish]
MSDS (hoja de seguridad de materiales)
Ketoconazol [Inn-Spanish]
Sintesis de referencia
J. Heeres et al., Patente de EE.UU.. 4,144,346 (1979)
Ketoconazol [Inn-Spanish]
Peso molecular
531.43 g/mol
Ketoconazol [Inn-Spanish]
Punto de fusion
146 oC
Ketoconazol [Inn-Spanish]
H2O Solubilidad
0,0866 mg / L
Ketoconazol [Inn-Spanish]
Estado
Solid
Ketoconazol [Inn-Spanish]
LogP
3.651
Ketoconazol [Inn-Spanish]
Formas de dosificacion
Tabletas: Shampoo, Crema, Suspensión
Ketoconazol [Inn-Spanish]
Indicacion
Para el tratamiento de las infecciones sistémicas por hongos siguientes: candidiasis, candidiasis mucocutánea crónica, candidiasis oral, candiduria, blastomicosis, coccidioidomicosis, histoplasmosis, cromomicosis, y paracoccidioidomicosis.
Ketoconazol [Inn-Spanish]
Farmacologia
Ketoconazol, como el clotrimazol, fluconazol, itraconazol y miconazol, es un agente antifúngico imidazólico.
Ketoconazol [Inn-Spanish]
Absorcion
Moderado
Ketoconazol [Inn-Spanish]
Toxicidad
Hepatotoxicidad, DL50 = 86 mg / kg (por vía oral en ratas)
Ketoconazol [Inn-Spanish]
Informacion de Pacientes
Shampoo: May be irritating to mucous membranes of the eyes and contact with this area should be
avoided.
There have been reports that use of the shampoo resulted in removal of the curl from permanently waved hair.
Tablet: Patients should be instructed to report any signs and symptoms which may suggest liver
dysfunction so that appropriate biochemical testing can be done. Such signs and symptoms may include unusual fatigue,
anorexia, nausea and/or vomiting, jaundice, dark urine or pale stools
Ketoconazol [Inn-Spanish]
Organismos afectados
Hongos